Catalog #: 3522-11
Keratin 6 Antibody

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 6, 16 and 17 are expressed in suprabasal keratinocytes of wounded epidermis. Keratin 6 is found in acrosyringeal keratinocytes in normal skin. LHK 6 is a very good marker for hyperproliferative keratinocytes.

Antigen:  Keratin 6

Clone number:  LHK6

Immunogen: 11 amino acid sequence GSSTIKYTTTS of K6b C terminal

Species Reactivity: Human

Host Species:  ---

Applications: ELISA, WB, IHC (F) (P) (A)

Isotype:  IgG2ak

References: Machesney M et al. 1998. Am. J. Pathol. 152:1133-1141.

                 Porter RM et al. 2000. Lab Invest. 80(11):1701-10.

Notes: ---

Quantity:  100μg